<div dir="ltr">1.  AlphaFold -- Deep Mind's project for protein folding/<div>Remember those SETI and BOINC projects where they attempted to do complex things, but we never heard of any successes?  It looks like AlphaFold has solved protein folding (well, within 90%), something that has not been possible since the first building blocks of life were created in a lab-1952.  I don't know if we've been able to do protein folding in the lab, but at least we can simulate the folding.</div><div><br></div><div>Should we dust off our protein folding software?</div><div><br></div><div>2. City Generators (I had a discussion about this with someone a while back).</div><div><br></div><div><a href="https://maps.probabletrain.com/#/">https://maps.probabletrain.com/#/</a></div><div><br></div><div>(there are more, google). Probably Christopher Alexander gets the credit here.</div><div><br></div><div>How do I write a declarative city generator? is something to think about.  We can do particle and rigid physics, right?  Alexander recommends a process which incorporates the 15 fundamental properties of life. "The Nature of Order"</div><div><br></div><div>John</div><div><br></div><div>We have to keep working harder to keep up, it seems.</div></div>